![]() ![]() ![]() There are approximately 470 entries anticipated for the WeatherTech Chicago Region® June Sprints®. This year’s Hoosier Racing Tire SCCA® Super Tour WeatherTech Chicago Region® June Sprints® represents the 65th successive running of this prestigious event at Road America, possibly making it the longest consecutively held road race in America. If you thought a pandemic would stop the June Sprints streak, you were wrong. Back then, the June Sprints was a component of the SCCA National Sports Car Championship, a series that determined SCCA champions prior to today’s Runoffs®. Read more about how to correctly acknowledge RSC content.It was 1956 when the first full season of racing began at Road America, and the Chicago Region June Sprints was part of that year’s schedule. Please go to the Copyright Clearance Center request page. In a third-party publication (excluding your thesis/dissertation for which permission is not required) ![]() If you want to reproduce the whole article If you are the author of this article, you do not need to request permission to reproduce figuresĪnd diagrams provided correct acknowledgement is given. Provided correct acknowledgement is given. If you are an author contributing to an RSC publication, you do not need to request permission To request permission to reproduce material from this article, please go to the The prototype CompleXima HCC Biochip allows their measurement with a good analytical reproducibility.Īnalytical validation of a Biochip prototype for integrated analysis of AFP-IgM and SCCA-IgM serum biomarkers in patients with liver cirrhosis and hepatocellular carcinoma ![]() Conclusions: AFP-IgM and SCCA-IgM increase in chronic liver disease. The combined evaluation of macrocomplexes with CompleXima in diagnosing HCC with respect to LC was associated with a sensitivity of 51.4% and a specificity of 48%. The sensitivity of AFP-IgM and SCCA-IgM associated with CompleXima in detecting patients with liver diseases was 47% and 46%, respectively. The thresholds for AFP-IgM and SCCA-IgM were calculated by means of ROC curves, fixing the specificity at 95%. Both biomarkers were higher in LC and HCC with respect to controls ( p < 0.001) with no difference between LC and HCC ( p = 0.864 for AFP-IgM and p = 0.214 for SCCA-IgM). Passing–Bablok showed that the Biochip under-estimated AFP-IgM (Intercept A: −165.06 95% CI: −313.11 to −51.32) and overestimated SCCA-IgM (Intercept A: 26.83 95% CI: 14.47–35.86) with respect to ELISAs. The comparison between the prototype and the ELISA test was studied by using the Bland–Altman method and Passing–Bablok regression analyses. The linearity interval for the CompleXima HCC Biochip was 50–300 AU mL −1 for AFP-IgM and SCCA-IgM. Results: the intra-assay coefficients of variation were lower than 12% and the inter-assay variations comprised between 14% and 21%. Methods: AFP- and SCCA-IgM were measured by both ELISA and CompleXima HCC Biochip in 39 blood donors and in 174 patients (102 liver cirrhosis – LC – and 72 hepatocellular carcinoma – HCC). Aim: this study evaluates the analytical and clinical performances of a new technology, CompleXima HCC Biochip, for the simultaneous serum measurement of alpha-fetoprotein-IgM (AFP-IgM) and squamous cell carcinoma antigen-IgM (SCCA-IgM). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |